PPP2R2B antibody

Catalog No. ABIN7184004

Product Details anti-PPP2R2B Antibody

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human PPP2R2B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Alternative Name: PPP2R2B (PPP2R2B Products)

Background:

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.

Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022].

Aliases: 2ABB_HUMAN antibody, B55 beta antibody, Beta isoform of regulatory subunit B55 protein phosphatase 2 antibody, MGC24888 antibody, PP2A B55beta antibody, PP2A PR55B antibody, PP2A subunit B B beta isoform antibody, PP2A subunit B B55 beta isoform antibody, PP2A subunit B isoform B55 beta antibody, PP2A subunit B isoform B55-beta antibody, PP2A subunit B isoform beta antibody, PP2A subunit B isoform PR55 beta antibody, PP2A subunit B isoform PR55-beta antibody, PP2A subunit B isoform R2 beta antibody, PP2A subunit B isoform R2-beta antibody, PP2A subunit B PR55 beta isoform antibody, PP2A subunit B R2 beta isoform antibody, Ppp2r2b antibody, PR2AB beta antibody, PR2AB55 beta antibody, PR2APR55 beta antibody, PR52B antibody, PR55 beta antibody, Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) beta isoform antibody, Protein phosphatase 2 (formerly 2A) regulatory subunit B beta isoform antibody, Protein phosphatase 2 regulatory subunit B antibody, Protein phosphatase 2 regulatory subunit B beta isoform antibody, SCA 12 antibody, SCA12 antibody, Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody, Serine/threonine protein phosphatase 2A neuronal isoform antibody, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody

UniProt: Q00005

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C