CDK11 antibody (N-Term)

Catalog No. ABIN7184423

This Rabbit Polyclonal antibody specifically detects CDK11 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CDK11 antibody (N-Term) (ABIN7184423)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDK11 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human CD2L1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDK11B

Background:

Background: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.

Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).
Eipers P.G., Genomics 13:613-621(1992).
Xiang J., J. Biol. Chem. 269:15786-15794(1994).

Aliases: CDK11B antibody, CDC2L1 antibody, CDK11 antibody, PITSLREA antibody, PK58 antibody, Cyclin-dependent kinase 11B antibody, EC 2.7.11.22 antibody, Cell division cycle 2-like protein kinase 1 antibody, CLK-1 antibody, Cell division protein kinase 11B antibody, Galactosyltransferase-associated protein kinase p58/GTA antibody, PITSLRE serine/threonine-protein kinase CDC2L1 antibody, p58 CLK-1 antibody

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase