CUX1 antibody (N-Term)

Catalog No. ABIN7184441

This Rabbit Polyclonal antibody specifically detects CUX1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CUX1 antibody (N-Term) (ABIN7184441)

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CUX1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human CUTL1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1

Background:

Background: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.

Neufeld E.J., Nat. Genet. 1:50-55(1992).
Gloeckner G., Genome Res. 8:1060-1073(1998).
Rong Zeng W., Gene 241:75-85(2000).

Aliases: CUX1 antibody, CUTL1Homeobox protein cut-like 1 antibody, CCAAT displacement protein antibody, CDP antibody, Homeobox protein cux-1 antibody

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process