GTF2IRD1 antibody (N-Term)

Catalog No. ABIN7184456

This Rabbit Polyclonal antibody specifically detects GTF2IRD1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for GTF2IRD1 antibody (N-Term) (ABIN7184456)

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2IRD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTF2IRD1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human GTF2IRD1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GTF2IRD1

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Alternative Name: GTF2IRD1

Background:

Background: May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 By similarity.

Yan X., Biochem. J. 345:749-757(2000).
Hillier L.W., Nature 424:157-164(2003).
Tussie-Luna M.I., Proc. Natl. Acad. Sci. U.S.A. 98:7789-7794(2001).

Aliases: CREAM1 antibody, General transcription factor II I repeat domain containing protein 1 antibody, General transcription factor II-I repeat domain-containing protein 1 antibody, General transcription factor III antibody, GT2D1_HUMAN antibody, GTF2I repeat domain containing protein 1 antibody, GTF2I repeat domain-containing protein 1 antibody, GTF2IRD1 antibody, GTF3 antibody, Muscle TFII I repeat domain-containing protein 1 antibody, Muscle TFII-I repeat domain-containing protein 1 antibody, MUSTRD1 antibody, MusTRD1/BEN antibody, RBAP2 antibody, Slow muscle fiber enhancer binding protein antibody, Slow-muscle-fiber enhancer-binding protein antibody, USE B1 binding protein antibody, USE B1-binding protein antibody, WBSCR11 antibody, WBSCR12 antibody, Williams Beuren syndrome chromosome region 11 protein antibody, Williams-Beuren syndrome chromosomal region 11 protein antibody, Williams-Beuren syndrome chromosomal region 12 protein antibody

UniProt: Q9UHL9