ANKRD28 antibody

Catalog No. ABIN7189809

This anti-ANKRD28 antibody is a Rabbit Polyclonal antibody detecting ANKRD28 in WB and ELISA. Suitable for Human.

Quick Overview for ANKRD28 antibody (ABIN7189809)

Target: ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD28 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANKRD28 Antibody

Purpose: ANKRD28 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human ANKRD28

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ANKRD28

Target: ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))

Alternative Name: ANKRD28

Background:

Background: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.

Aliases: ANKRD28 antibody, KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody, PP6-ARS-A antibody, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody, Ankyrin repeat domain-containing protein 28 antibody, Phosphatase interactor targeting protein hnRNP K antibody, PITK antibody

UniProt: O15084