FAT4 antibody

Catalog No. ABIN7190632

This Rabbit Polyclonal antibody specifically detects FAT4 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for FAT4 antibody (ABIN7190632)

Target: FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAT4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FAT4 Antibody

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human FAT4

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAT4

Target: FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

Alternative Name: FAT4

Background:

Background: FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Aliases: Cadherin family member 14 antibody, Cadherin related family member 11 antibody, CDHF14 antibody, CDHR11 antibody, FAT atypical cadherin 4 antibody, FAT J antibody, FAT tumor suppressor homolog 4 antibody, Fat-like cadherin protein FAT-J antibody, FAT4 antibody, FAT4_HUMAN antibody, FATJ antibody, hFat4 antibody, HKLLS2 antibody, Nbla00548 antibody, Protocadherin Fat 4 antibody, Putative protein product of Nbla00548 antibody, VMLDS2 antibody

UniProt: Q6V0I7