SCNN1A antibody

Catalog No. ABIN7192286

The Rabbit Polyclonal anti-SCNN1A antibody has been validated for IHC and ELISA. It is suitable to detect SCNN1A in samples from Human.

Quick Overview for SCNN1A antibody (ABIN7192286)

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SCNN1A Antibody

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SCNN1A

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCNN1A

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Alternative Name: SCNN1A

Background:

Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: Alpha ENaC 2 antibody, Alpha ENaC antibody, Alpha NaCH antibody, Alpha-ENaC antibody, Alpha-NaCH antibody, Amiloride sensitive epithelial sodium channel alpha subunit antibody, Amiloride sensitive sodium channel subunit alpha antibody, Amiloride-sensitive sodium channel subunit alpha antibody, ENaCA antibody, ENaCalpha antibody, Epithelial Na(+) channel subunit alpha antibody, Epithelial Na+ channel subunit alpha antibody, FLJ21883 antibody, Nonvoltage gated sodium channel 1 subunit alpha antibody, Nonvoltage-gated sodium channel 1 subunit alpha antibody, SCNEA antibody, SCNN 1 antibody, SCNN1 antibody, Scnn1a antibody, SCNNA_HUMAN antibody, Sodium channel nonvoltage gated 1 alpha antibody

UniProt: P37088