ABCB1 antibody (AA 1149-1280)
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- Target See all ABCB1 Antibodies
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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Binding Specificity
- AA 1149-1280
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ABCB1 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CD243 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD243 (AA: 1149-1280) expressed in E. Coli.
- Clone
- 4G6F4
- Isotype
- IgG1
- Top Product
- Discover our top product ABCB1 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 621-650), (Middle Region) antibody
ABCB1 Reactivity: Human, Mouse, Rat IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibodyABCB1 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 2C7 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibodyABCB1 Reactivity: Human IHC, IHC (p) Host: Mouse Monoclonal 5B3 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibodyABCB1 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 236-297) antibodyABCB1 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 632-693) antibodyABCB1 Reactivity: Human ELISA Host: Mouse Monoclonal 6G11C12 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 863-912) antibodyABCB1 Reactivity: Human, Mouse, Rat, Rabbit, Hamster WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Middle Region) antibodyABCB1 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Sheep, Pig, Guinea Pig, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 647-677) antibodyABCB1 Reactivity: Human WB Host: Rabbit Polyclonal RB2208 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibody (APC)ABCB1 Reactivity: Human FACS Host: Mouse Monoclonal UIC2 APC
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- Alternative Name
- CD243 (ABCB1 Products)
- Background
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Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Aliases: ABCB1, CLCS, MDR1, P-GP, PGY1, ABC20, GP170
- Molecular Weight
- 141.1kDa
- Gene ID
- 5243
- UniProt
- P08183
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