COL1A2 antibody (AA 23-79)

Catalog No. ABIN7193541

This anti-COL1A2 antibody is a Mouse Monoclonal antibody detecting COL1A2 in ELISA, ICC and FACS. Suitable for Human.

Quick Overview for COL1A2 antibody (AA 23-79) (ABIN7193541)

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This COL1A2 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 4D1A7

Product Details anti-COL1A2 Antibody

Binding Specificity: AA 23-79

Purpose: COL1A2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human COL1A2 (AA: 23-79) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for COL1A2

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Alternative Name: COL1A2

Background:

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Molecular Weight: 129 kDa

Gene ID: 1278

UniProt: P08123