Selectin E/CD62e antibody

Catalog No. ABIN7193755

This Mouse Monoclonal antibody specifically detects Selectin E/CD62e in ELISA, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for Selectin E/CD62e antibody (ABIN7193755)

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Selectin E/CD62e antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 5A8C6

Product Details anti-Selectin E/CD62e Antibody

Purpose: CD62E Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD62E (AA: extra(22-162)) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Alternative Name: CD62E

Background:

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

Molecular Weight: 66.7 kDa

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling