TRIB2 antibody (AA 1-200)

Catalog No. ABIN7193903

The Mouse Monoclonal anti-TRIB2 antibody has been validated for ELISA, IHC, FACS and ICC. It is suitable to detect TRIB2 in samples from Human.

Quick Overview for TRIB2 antibody (AA 1-200) (ABIN7193903)

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIB2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 6A12A12

Product Details anti-TRIB2 Antibody

Binding Specificity: AA 1-200

Purpose: TRIB2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TRIB2 (AA: 1-200) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TRIB2

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Alternative Name: TRIB2

Background:

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

Molecular Weight: 38.8 kDa

Gene ID: 28951