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TSG101 antibody (AA 167-374)

This Mouse Monoclonal antibody specifically detects TSG101 in IHC, ELISA and FACS. It exhibits reactivity toward Human.
Catalog No. ABIN7193932

Quick Overview for TSG101 antibody (AA 167-374) (ABIN7193932)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

  • 77
  • 43
  • 32
  • 11
  • 10
  • 9
  • 8
  • 8
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Host

  • 68
  • 14
Mouse

Clonality

  • 57
  • 25
Monoclonal

Conjugate

  • 57
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TSG101 antibody is un-conjugated

Application

  • 68
  • 33
  • 29
  • 16
  • 16
  • 13
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone

8E10D10
  • Binding Specificity

    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-374

    Purpose

    TSG101 Antibody

    Purification

    Purified antibody

    Immunogen

    Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.

    Isotype

    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    TSG101

    Background

    The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

    Molecular Weight

    44 kDa

    Gene ID

    7251

    UniProt

    Q99816
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