ATF5 antibody (acLys29)
Quick Overview for ATF5 antibody (acLys29) (ABIN7212588)
Target
See all ATF5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- acLys29
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Purpose
- ATF-5 (Acetyl Lys29) Polyclonal Antibody
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Specificity
- Acetyl-ATF-5 (K29) Polyclonal Antibody detects endogenous levels of ATF-5 protein only when acetylated at K29.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the human ATF-5 around the acetylation site of K29
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ATF5 (Activating Transcription Factor 5 (ATF5))
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Alternative Name
- ATF-5
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Background
- Rabbit Anti-ATF-5 (Acetyl Lys29) Polyclonal Antibody,ATF5, ATFX, Cyclic AMP-dependent transcription factor ATF-5, cAMP-dependent transcription factor ATF-5, Activating transcription factor 5, Transcription factor ATFx,ATF5 or Activating transcription factor 5, binds to cAMP inducible promoters and is involved in gene transcription. Activating transcription factor 5 binds the cAMP response element (CRE)(consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis.,Cyclic AMP-dependent transcription factor ATF-5
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Gene ID
- 22809
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UniProt
- Q9Y2D1
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Pathways
- Myometrial Relaxation and Contraction
Target
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