ADA antibody (AA 80-160)
Quick Overview for ADA antibody (AA 80-160) (ABIN7227210)
Target
See all ADA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 80-160
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Purpose
- ADA Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of ADA protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human ADA protein at AA range: 80-160
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ADA (Adenosine Deaminase (ADA))
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Alternative Name
- ADA
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Background
- Rabbit Anti-ADA Polyclonal Antibody,Adenosine deaminase, Adenosine aminohydrolase,ADA (Adenosine Deaminase) is a Protein Coding gene. Diseases associated with ADA include Severe Combined Immunodeficiency Due To Ada Deficiency and Adenosine Deaminase Deficiency. Among its related pathways are Metabolism and One carbon pool by folate. ADA encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for ADA and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.,ADA
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Gene ID
- 100
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UniProt
- P00813
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
Target
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