AGXT2 antibody (AA 340-420)

Catalog No. ABIN7227242

The Rabbit Polyclonal anti-AGXT2 antibody has been validated for WB and ELISA. It is suitable to detect AGXT2 in samples from Human, Mouse and Rat.

Quick Overview for AGXT2 antibody (AA 340-420) (ABIN7227242)

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AGXT2 Antibody

Binding Specificity: AA 340-420

Purpose: AGT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AGT2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human AGT2 protein at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Alternative Name: AGT2

Background: Rabbit Anti-AGT2 Polyclonal Antibody,Alanine--glyoxylate aminotransferase 2, mitochondrial, AGT 2, (R)-3-amino-2methylpropionate--pyruvate transaminase, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-AIBAT,The protein encoded by AGXT2 is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in AGXT2 affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants.,AGT2

Gene ID: 64902

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process