Angiomotin antibody (AA 710-790)
Quick Overview for Angiomotin antibody (AA 710-790) (ABIN7227280)
Target
See all Angiomotin (AMOT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 710-790
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Purpose
- AMOT Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of AMOT protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human AMOT protein at AA range: 710-790
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Angiomotin (AMOT)
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Alternative Name
- AMOT
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Background
- Rabbit Anti-AMOT Polyclonal Antibody,Angiomotin,AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.,AMOT
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Gene ID
- 154796
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UniProt
- Q4VCS5
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Pathways
- Cell-Cell Junction Organization, Regulation of Cell Size
Target
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