BCL2L12 antibody (AA 60-140)

Catalog No. ABIN7225300

The Rabbit Polyclonal anti-BCL2L12 antibody has been validated for WB and ELISA. It is suitable to detect BCL2L12 in samples from Human and Mouse.

Quick Overview for BCL2L12 antibody (AA 60-140) (ABIN7225300)

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCL2L12 Antibody

Binding Specificity: AA 60-140

Purpose: BCL2L12 Polyclonal Antibody

Specificity: BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BCL2L12 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BCL2L12

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Alternative Name: BCL2L12

Background: Rabbit Anti-BCL2L12 Polyclonal Antibody,BCL2L12, BPR, Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein,BCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome 3. Alternative splicing results in multiple transcript variants.,Bcl-2-like protein 12

Gene ID: 83596

UniProt: Q9HB09