BMX antibody (AA 30-110)

Catalog No. ABIN7213834

This Rabbit Polyclonal antibody specifically detects BMX in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for BMX antibody (AA 30-110) (ABIN7213834)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BMX Antibody

Binding Specificity: AA 30-110

Purpose: Bmx Polyclonal Antibody

Specificity: Bmx Polyclonal Antibody detects endogenous levels of Bmx protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Bmx at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Alternative Name: Bmx

Background: Rabbit Anti-Bmx Polyclonal Antibody,BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38,BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein (BMX non-receptor tyrosine kinase) contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.,Cytoplasmic tyrosine-protein kinase BMX

Molecular Weight: observerd band 75kDa

Gene ID: 660

UniProt: P51813