Cadherin-16 antibody (AA 750-830)

Catalog No. ABIN7213904

This anti-Cadherin-16 antibody is a Rabbit Polyclonal antibody detecting Cadherin-16 in WB, IF, ELISA and IHC (p). Suitable for Human.

Quick Overview for Cadherin-16 antibody (AA 750-830) (ABIN7213904)

Target: Cadherin-16 (CDH16)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin-16 Antibody

Binding Specificity: AA 750-830

Purpose: Cadherin-16 Polyclonal Antibody

Specificity: Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Cadherin-16 at AA range: 750-830

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Cadherin-16

Background: Rabbit Anti-Cadherin-16 Polyclonal Antibody,CDH16, Cadherin-16, Kidney-specific cadherin, Ksp-cadherin,CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,Cadherin-16

Molecular Weight: observerd band 90kDa

Gene ID: 1014

UniProt: O75309