CILP antibody

Catalog No. ABIN7227908

This anti-CILP antibody is a Rabbit Polyclonal antibody detecting CILP in WB and ELISA. Suitable for Human.

Quick Overview for CILP antibody (ABIN7227908)

Target: CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CILP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CILP Antibody

Purpose: CILP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CILP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CILP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CILP

Target: CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))

Alternative Name: CILP1

Background: Rabbit Anti-CILP1 Polyclonal Antibody,Cartilage intermediate layer protein 1, CILP-1, Cartilage intermediate-layer protein,Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. CILP encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.,CILP1

Molecular Weight: observerd band 130kDa

Gene ID: 8483

UniProt: O75339