CSNK1A1 antibody (AA 100-180)
Quick Overview for CSNK1A1 antibody (AA 100-180) (ABIN7213950)
Target
See all CSNK1A1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-180
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Purpose
- Casein Kinase Iα Polyclonal Antibody
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Specificity
- Casein Kinase Iα Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Casein Kinase Ialpha at AA range: 100-180
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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Alternative Name
- Casein Kinase Ialpha
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Background
- Rabbit Anti-Casein Kinase Iα Polyclonal Antibody,CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1,Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.,Casein kinase I isoform alpha
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Molecular Weight
- observerd band 35kDa
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Gene ID
- 1452
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UniProt
- P48729
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Pathways
- WNT Signaling, Hedgehog Signaling
Target
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