Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) antibody

Catalog No. ABIN7202052

The Rabbit Polyclonal anti-not_set antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect not_set in samples from Rat and Mouse.

Quick Overview for Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) antibody (ABIN7202052)

Target: Caspase 6 p18

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 120-200, Cleaved-Asp162

Purpose: Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody

Specificity: Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D162.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of mouse Caspase-6 p18 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: Caspase 6 p18

Alternative Name: Caspase-6 p18

Background: Rabbit Anti-Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody,CASP6, MCH2, Caspase-6, CASP-6, Apoptotic protease Mch-2,CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme.Caspase 6 is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.,Caspase-6

Gene ID: 839

UniProt: P55212