Caveolin 2 antibody (pTyr27)

Catalog No. ABIN7225558

This Rabbit Polyclonal antibody specifically detects Caveolin 2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Caveolin 2 antibody (pTyr27) (ABIN7225558)

Target: Caveolin 2 (CAV2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Caveolin 2 Antibody

Binding Specificity: pTyr27

Purpose: Caveolin-2 (phospho Tyr27) Polyclonal Antibody

Specificity: Phospho-Caveolin-2 (Y27) Polyclonal Antibody detects endogenous levels of Caveolin-2 protein only when phosphorylated at Y27.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Caveolin-2 Phospho-Tyr27

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: Caveolin-2

Background: Rabbit Anti-Caveolin-2 (phospho Tyr27) Polyclonal Antibody,CAV2, Caveolin-2,The protein encoded by CAV2 (caveolin 2) is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV2 and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for CAV2. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID: 11238462).,Caveolin-2

Molecular Weight: observerd band 26kDa

Gene ID: 858

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development