CEP170 antibody (AA 670-750)

Catalog No. ABIN7214144

This anti-CEP170 antibody is a Rabbit Polyclonal antibody detecting CEP170 in WB, ELISA and IHC (p). Suitable for Human.

Quick Overview for CEP170 antibody (AA 670-750) (ABIN7214144)

Target: CEP170 (Centrosomal Protein 170kDa (CEP170))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP170 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CEP170 Antibody

Binding Specificity: AA 670-750

Purpose: CEP170 Polyclonal Antibody

Specificity: CEP170 Polyclonal Antibody detects endogenous levels of CEP170 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CEP170 at AA range: 670-750

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CEP170

Target: CEP170 (Centrosomal Protein 170kDa (CEP170))

Alternative Name: CEP170

Background: Rabbit Anti-CEP170 Polyclonal Antibody,CEP170, FAM68A, KAB, KIAA0470, Centrosomal protein of 170 kDa, Cep170, KARP-1-binding protein, KARP1-binding protein,The product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.,Centrosomal protein of 170 kDa

Molecular Weight: observerd band 160kDa

Gene ID: 9859

UniProt: Q5SW79