CCR3 antibody (N-Term)

Catalog No. ABIN7218114

This Rabbit Polyclonal antibody specifically detects CCR3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CCR3 antibody (N-Term) (ABIN7218114)

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCR3 Antibody

Binding Specificity: N-Term

Purpose: CKR-3 Polyclonal Antibody

Specificity: CKR-3 Polyclonal Antibody detects endogenous levels of CKR-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CKR-3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CCR3

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Alternative Name: CKR-3

Background: Rabbit Anti-CKR-3 Polyclonal Antibody,CCR3, CMKBR3, C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Eosinophil eotaxin receptor, CD193,C-C motif chemokine receptor 3 encoded by CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.,C-C chemokine receptor type 3

Molecular Weight: observerd band 41kDa

Gene ID: 1232

UniProt: P51677