CCBP2 antibody (AA 310-390)
Quick Overview for CCBP2 antibody (AA 310-390) (ABIN7214180)
Target
See all CCBP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 310-390
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Purpose
- Chemokine Receptor D6 Polyclonal Antibody
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Specificity
- Chemokine Receptor D6 Polyclonal Antibody detects endogenous levels of Chemokine Receptor D6 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human Chemokine Receptor D6 at AA range: 310-390
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CCBP2 (Chemokine Binding Protein 2 (CCBP2))
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Alternative Name
- Chemokine Receptor D6
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Background
- Rabbit Anti-Chemokine Receptor D6 Polyclonal Antibody,CCBP2, CCR10, CMKBR9, Chemokine-binding protein 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein D6,CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. CCBP2 is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. CCBP2 is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.,Chemokine-binding protein 2
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Molecular Weight
- observerd band 34kDa
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Gene ID
- 1238
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UniProt
- O00590
Target
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