CNTNAP1 antibody
Quick Overview for CNTNAP1 antibody (ABIN7227990)
Target
See all CNTNAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- CNTP1 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of CNTP1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human CNTP1 protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
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Alternative Name
- CNTP1
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Background
- Rabbit Anti-CNTP1 Polyclonal Antibody,Contactin-associated protein 1, Caspr, Caspr1, Neurexin IV, Neurexin-4, p190,CNTNAP1 product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for contactin-associated protein, includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.,CNTP1
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Molecular Weight
- observerd band 152kDa
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Gene ID
- 8506
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UniProt
- P78357
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Pathways
- Cell-Cell Junction Organization
Target
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