COX17 antibody (AA 1-80)

Catalog No. ABIN7214302

This Rabbit Polyclonal antibody specifically detects COX17 in ELISA, WB, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COX17 antibody (AA 1-80) (ABIN7214302)

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX17 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-COX17 Antibody

Binding Specificity: AA 1-80

Purpose: COX17 Polyclonal Antibody

Specificity: COX17 Polyclonal Antibody detects endogenous levels of COX17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human COX17 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for COX17

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Alternative Name: COX17

Background: Rabbit Anti-COX17 Polyclonal Antibody,COX17, Cytochrome c oxidase copper chaperone,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92 % amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.,Cytochrome c oxidase copper chaperone

Molecular Weight: observerd band 7kDa

Gene ID: 10063

UniProt: Q14061