CELF1 antibody (AA 40-120)

Catalog No. ABIN7214376

This anti-CELF1 antibody is a Rabbit Polyclonal antibody detecting CELF1 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for CELF1 antibody (AA 40-120) (ABIN7214376)

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CELF1 Antibody

Binding Specificity: AA 40-120

Purpose: CUG-BP1 Polyclonal Antibody

Specificity: CUG-BP1 Polyclonal Antibody detects endogenous levels of CUG-BP1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CUG-BP1 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CELF1

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Alternative Name: CUG-BP1

Background: Rabbit Anti-CUG-BP1 Polyclonal Antibody,CELF1, BRUNOL2, CUGBP, CUGBP1, NAB50, CUGBP Elav-like family member 1, CELF-1, 50 kDa nuclear polyadenylated RNA-binding protein, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, Dead,Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.,CUGBP Elav-like family member 1

Molecular Weight: observerd band 52kDa

Gene ID: 10658

UniProt: Q92879

Pathways: Ribonucleoprotein Complex Subunit Organization