Cullin 4A antibody (AA 590-670)
Quick Overview for Cullin 4A antibody (AA 590-670) (ABIN7228098)
Target
See all Cullin 4A (CUL4A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 590-670
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Purpose
- CUL4A Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of CUL4A protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human CUL4A protein at AA range: 590-670
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cullin 4A (CUL4A)
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Alternative Name
- CUL4A
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Background
- Rabbit Anti-CUL4A Polyclonal Antibody,Cullin-4A, CUL-4A,CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins. CUL4A is a Protein Coding gene. Diseases associated with CUL4A include Xeroderma Pigmentosum Group E and Xeroderma Pigmentosum, Variant Type. Among its related pathways are Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template and Transcription-Coupled Nucleotide Excision Repair (TC-NER).,CUL4A
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Molecular Weight
- observerd band 83kDa
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Gene ID
- 8451
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UniProt
- Q13619
Target
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