DOCK11 antibody

Catalog No. ABIN7228270

This Rabbit Polyclonal antibody specifically detects DOCK11 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for DOCK11 antibody (ABIN7228270)

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DOCK11 Antibody

Purpose: DOC11 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DOC11 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human DOC11 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Alternative Name: DOC11

Background: Rabbit Anti-DOC11 Polyclonal Antibody,Dedicator of cytokinesis protein 11, Dedicator of cytokinesis protein 11, ACG, Zizimin-2,DOCK11 (Dedicator Of Cytokinesis 11) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and G-protein signaling_Regulation of CDC42 activity. Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.,DOC11

Molecular Weight: observerd band 228kDa

Gene ID: 139818

UniProt: Q5JSL3