DOCK2 antibody (Internal Region)

Catalog No. ABIN7220070

The Rabbit Polyclonal anti-DOCK2 antibody has been validated for ELISA and IHC (p). It is suitable to detect DOCK2 in samples from Human, Mouse and Rat.

Quick Overview for DOCK2 antibody (Internal Region) (ABIN7220070)

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DOCK2 Antibody

Binding Specificity: Internal Region

Purpose: DOCK2 Polyclonal Antibody

Specificity: DOCK2 Polyclonal Antibody detects endogenous levels of DOCK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DOCK2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Alternative Name: DOCK2

Background: Rabbit Anti-DOCK2 Polyclonal Antibody,DOCK2, KIAA0209, Dedicator of cytokinesis protein 2,Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.,Dedicator of cytokinesis protein 2

Gene ID: 1794

UniProt: Q92608