DNA polymerase delta catalytic subunit (POL3) (AA 380-460) antibody
Quick Overview for DNA polymerase delta catalytic subunit (POL3) (AA 380-460) antibody (ABIN7219114)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 380-460
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Purpose
- DNA pol δ3 Polyclonal Antibody
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Specificity
- DNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human DNA pol delta3 at AA range: 380-460
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DNA polymerase delta catalytic subunit (POL3)
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Alternative Name
- DNA pol delta3
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Background
- Rabbit Anti-DNA pol δ3 Polyclonal Antibody,POLD3, KIAA0039, DNA polymerase delta subunit 3, DNA polymerase delta subunit p66,POLD3 encodes the 66- kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The DNA polymerase delta 3, accessory subunit plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.,DNA polymerase delta subunit 3
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Molecular Weight
- observerd band 51kDa
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Gene ID
- 10714
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UniProt
- Q15054
Target
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