Ectodysplasin A antibody (Internal Region)

Catalog No. ABIN7226662

This anti-Ectodysplasin A antibody is a Rabbit Polyclonal antibody detecting Ectodysplasin A in WB, ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for Ectodysplasin A antibody (Internal Region) (ABIN7226662)

Target: Ectodysplasin A (EDA)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Ectodysplasin A Antibody

Binding Specificity: Internal Region

Purpose: EDA Polyclonal Antibody

Specificity: EDA Polyclonal Antibody detects endogenous levels of EDA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human EDA

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA

Background: Rabbit Anti-EDA Polyclonal Antibody,EDA, ED1, EDA2, Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein,The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for EDA.,Ectodysplasin-A

Molecular Weight: observerd band 42kDa

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation