ERAS antibody (AA 160-240)

Catalog No. ABIN7221562

This Rabbit Polyclonal antibody specifically detects ERAS in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for ERAS antibody (AA 160-240) (ABIN7221562)

Target: ERAS (ES cell expressed Ras (ERAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ERAS Antibody

Binding Specificity: AA 160-240

Purpose: E-Ras Polyclonal Antibody

Specificity: E-Ras Polyclonal Antibody detects endogenous levels of E-Ras protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human E-Ras at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ERAS

Target: ERAS (ES cell expressed Ras (ERAS))

Alternative Name: E-Ras

Background: Rabbit Anti-E-Ras Polyclonal Antibody,ERAS, HRAS2, HRASP, GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras,ERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.,GTPase Eras

Molecular Weight: observerd band 25kDa

Gene ID: 3266

UniProt: Q7Z444