FKBP3 antibody (AA 140-220)

Catalog No. ABIN7228540

This Rabbit Polyclonal antibody specifically detects FKBP3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for FKBP3 antibody (AA 140-220) (ABIN7228540)

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FKBP3 Antibody

Binding Specificity: AA 140-220

Purpose: FKBP3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FKBP3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FKBP3 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FKBP3

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Alternative Name: FKBP3

Background: Rabbit Anti-FKBP3 Polyclonal Antibody,Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25 , Rapamycin-selective 25 kDa immunophilin, Rotamase,The protein encoded by FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.,FKBP3

Molecular Weight: observerd band 24kDa

Gene ID: 2287

UniProt: Q00688