Fukutin antibody (AA 111-160)

Catalog No. ABIN7228550

This Rabbit Polyclonal antibody specifically detects Fukutin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Fukutin antibody (AA 111-160) (ABIN7228550)

Target: Fukutin (FKTN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fukutin Antibody

Binding Specificity: AA 111-160

Purpose: FKTN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FKTN protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FKTN protein at AA range: 111-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN

Background: Rabbit Anti-FKTN Polyclonal Antibody,Fukutin, Fukuyama-type congenital muscular dystrophy protein,The protein encoded by FKTN is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in FKTN are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for FKTN.,FKTN

Molecular Weight: observerd band 50kDa

Gene ID: 2218

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process