GPR124 antibody (AA 1120-1200)

Catalog No. ABIN7220942

The Rabbit Polyclonal anti-GPR124 antibody has been validated for ELISA, WB and IF. It is suitable to detect GPR124 in samples from Human and Mouse.

Quick Overview for GPR124 antibody (AA 1120-1200) (ABIN7220942)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR124 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GPR124 Antibody

Binding Specificity: AA 1120-1200

Purpose: GPR124 Polyclonal Antibody

Specificity: GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human GPR124 at AA range: 1120-1200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Alternative Name: GPR124

Background: Rabbit Anti-GPR124 Polyclonal Antibody,GPR124, KIAA1531, TEM5, G-protein coupled receptor 124, Tumor endothelial marker 5,ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene. Among its related pathways are Integrins in angiogenesis. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRA1. ndothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed: 16982628).,G-protein coupled receptor 124

Molecular Weight: observerd band 145kDa

Gene ID: 25960

UniProt: Q96PE1