GRK6 antibody (AA 10-90)

Catalog No. ABIN7221274

This anti-GRK6 antibody is a Rabbit Polyclonal antibody detecting GRK6 in WB, ELISA and IF. Suitable for Human, Mouse and Rat.

Quick Overview for GRK6 antibody (AA 10-90) (ABIN7221274)

Target: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GRK6 Antibody

Binding Specificity: AA 10-90

Purpose: GRK 6 Polyclonal Antibody

Specificity: GRK 6 Polyclonal Antibody detects endogenous levels of GRK 6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GRK 6 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GRK6

Target: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Alternative Name: GRK 6

Background: Rabbit Anti-GRK 6 Polyclonal Antibody,GRK6, GPRK6, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6,GRK6 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The G protein-coupled receptor kinase 6 phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for GRK6.,G protein-coupled receptor kinase 6

Molecular Weight: observerd band 65kDa

Gene ID: 2870

UniProt: P43250

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity