Glutaredoxin 1 antibody (AA 40-120)

Catalog No. ABIN7228674

This anti-Glutaredoxin 1 antibody is a Rabbit Polyclonal antibody detecting Glutaredoxin 1 in WB and ELISA. Suitable for Human.

Quick Overview for Glutaredoxin 1 antibody (AA 40-120) (ABIN7228674)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Glutaredoxin 1 Antibody

Binding Specificity: AA 40-120

Purpose: GLRX1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GLRX1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GLRX1 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX1

Background: Rabbit Anti-GLRX1 Polyclonal Antibody,Glutaredoxin-1, Thioltransferase-1, TTase-1,GLRX encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.,GLRX1

Molecular Weight: observerd band 11kDa

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis