GRAP2 antibody (AA 90-170)

Catalog No. ABIN7214992

The Rabbit Polyclonal anti-GRAP2 antibody has been validated for WB and ELISA. It is suitable to detect GRAP2 in samples from Human.

Quick Overview for GRAP2 antibody (AA 90-170) (ABIN7214992)

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GRAP2 Antibody

Binding Specificity: AA 90-170

Purpose: Gads Polyclonal Antibody

Specificity: Gads Polyclonal Antibody detects endogenous levels of Gads protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Gads at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GRAP2

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Alternative Name: Gads

Background: Rabbit Anti-Gads Polyclonal Antibody,GRAP2, GADS, GRB2L, GRID, GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein Grp,GRAP2 encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. GRB2-related adapter protein 2 interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,GRB2-related adapter protein 2

Molecular Weight: observerd band 38kDa

Gene ID: 9402

UniProt: O75791

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway