GUCY1B3 antibody (AA 10-90)

Catalog No. ABIN7215042

This anti-GUCY1B3 antibody is a Rabbit Polyclonal antibody detecting GUCY1B3 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for GUCY1B3 antibody (AA 10-90) (ABIN7215042)

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GUCY1B3 Antibody

Binding Specificity: AA 10-90

Purpose: GCS-β-1 Polyclonal Antibody

Specificity: GCS-β-1 Polyclonal Antibody detects endogenous levels of GCS-β-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GCS-beta-1 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GUCY1B3

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Alternative Name: GCS-beta-1

Background: Rabbit Anti-GCS-β-1 Polyclonal Antibody,GUCY1B3, GUC1B3, GUCSB3, GUCY1B1, Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit,GUCY1B3 encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). Guanylate cyclase soluble subunit beta-1 contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.,Guanylate cyclase soluble subunit beta-1

Molecular Weight: observerd band 70kDa

Gene ID: 2983

UniProt: Q02153

Pathways: Transition Metal Ion Homeostasis