Inhibin alpha antibody (AA 211-260)

Catalog No. ABIN7229146

This Rabbit Polyclonal antibody specifically detects Inhibin alpha in ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Inhibin alpha antibody (AA 211-260) (ABIN7229146)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Inhibin alpha Antibody

Binding Specificity: AA 211-260

Purpose: Inhibin α Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Inhibin α

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Inhibin alpha protein at AA range: 211-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: Inhibin alpha

Background: Rabbit Anti-Inhibin α Polyclonal Antibody,Inhibin alpha chain,INHA encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in INHA may be associated with male infertility and premature ovarian failure in female human patients. INHA (Inhibin Alpha Subunit) is a Protein Coding gene. Diseases associated with INHA include Multidrug-Resistant Tuberculosis and Cystadenoma. Among its related pathways are Peptide hormone metabolism and Ovarian Infertility Genes.,Inhibin α

Gene ID: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion