Id2 antibody (AA 21-70)

Catalog No. ABIN7229010

This Rabbit Polyclonal antibody specifically detects Id2 in ELISA and WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Id2 antibody (AA 21-70) (ABIN7229010)

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Id2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Id2 Antibody

Binding Specificity: AA 21-70

Purpose: ID2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ID2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ID2 protein at AA range: 21-70

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Alternative Name: ID2

Background: Rabbit Anti-ID2 Polyclonal Antibody,DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, bHLHb26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2,The protein encoded by ID2 belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of ID2 is located on chromosome 3.,ID2

Molecular Weight: observerd band 14kDa

Gene ID: 3398

UniProt: Q02363