ITLN1/Omentin antibody (AA 110-190)

Catalog No. ABIN7229202

This Rabbit Polyclonal antibody specifically detects ITLN1/Omentin in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ITLN1/Omentin antibody (AA 110-190) (ABIN7229202)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITLN1/Omentin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITLN1/Omentin Antibody

Binding Specificity: AA 110-190

Purpose: ITLN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ITLN1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ITLN1 protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ITLN1/Omentin

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Alternative Name: ITLN1

Background: Rabbit Anti-ITLN1 Polyclonal Antibody,Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin,ITLN1 (Intelectin 1) is a Protein Coding gene. Diseases associated with ITLN1 include Obesity and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is ITLN2. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K. neumoniae, S. neumoniae, Y. estis, P. irabilis and P. ulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).,ITLN1

Molecular Weight: observerd band 34kDa

Gene ID: 55600

UniProt: Q8WWA0