IL18RAP antibody (AA 291-340)

Catalog No. ABIN7227708

This anti-IL18RAP antibody is a Rabbit Polyclonal antibody detecting IL18RAP in ELISA and IHC (p). Suitable for Human.

Quick Overview for IL18RAP antibody (AA 291-340) (ABIN7227708)

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18RAP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL18RAP Antibody

Binding Specificity: AA 291-340

Purpose: CD218b Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD218b

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CD218b protein at AA range: 291-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: CD218b

Background: Rabbit Anti-CD218b Polyclonal Antibody,Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, IL-18RAcP, Accessory protein-like, AcPL, CD218 antigen-like family member B, CDw218b, IL-1R accessory protein-like, IL-1RAcPL, Interleukin-1 receptor 7, IL-1R-7, IL-1R7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, IL-18R-beta, IL-18Rbeta, CD antigen CD218b,The protein encoded by IL18RAP is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in IL18RAP are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of IL18RAP have been described, but their full-length nature is not known.,CD218b

Gene ID: 8807

UniProt: O95256