MMP10 antibody (Cleaved-Phe99)

Catalog No. ABIN7212484

This anti-MMP10 antibody is a Rabbit Polyclonal antibody detecting MMP10 in WB and ELISA. Suitable for Human.

Quick Overview for MMP10 antibody (Cleaved-Phe99) (ABIN7212484)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MMP10 Antibody

Binding Specificity: AA 50-130, Cleaved-Phe99

Purpose: Cleaved-MMP-10 (F99) Polyclonal Antibody

Specificity: Cleaved-MMP-10 (F99) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-10 protein resulting from cleavage adjacent to F99.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MMP-10 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP-10

Background: Rabbit Anti-Cleaved-MMP-10 (F99) Polyclonal Antibody,MMP10, STMY2, Stromelysin-2, SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2,MMP10 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease (matrix metallopeptidase 10) breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. MMP10 is part of a cluster of MMP genes on chromosome 11.,Stromelysin-2

Molecular Weight: observerd band 43kDa

Gene ID: 4319

UniProt: P09238