MC4R antibody (AA 250-330)

Catalog No. ABIN7222392

The Rabbit Polyclonal anti-MC4R antibody has been validated for ELISA, WB and IHC (p). It is suitable to detect MC4R in samples from Human, Rat and Mouse.

Quick Overview for MC4R antibody (AA 250-330) (ABIN7222392)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MC4R Antibody

Binding Specificity: AA 250-330

Purpose: MC4-R Polyclonal Antibody

Specificity: MC4-R Polyclonal Antibody detects endogenous levels of MC4-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human MC4-R at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4-R

Background: Rabbit Anti-MC4-R Polyclonal Antibody,MC4R, Melanocortin receptor 4, MC4-R,The protein encoded by MC4R is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.,Melanocortin receptor 4

Molecular Weight: observerd band 37kDa

Gene ID: 4160

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour