MAGED2 antibody (AA 120-200)

Catalog No. ABIN7229540

This Rabbit Polyclonal antibody specifically detects MAGED2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MAGED2 antibody (AA 120-200) (ABIN7229540)

Target: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAGED2 Antibody

Binding Specificity: AA 120-200

Purpose: MAGD2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGD2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MAGD2 protein at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MAGED2

Target: MAGED2 (Melanoma Antigen Family D, 2 (MAGED2))

Alternative Name: MAGD2

Background: Rabbit Anti-MAGD2 Polyclonal Antibody,Melanoma-associated antigen D2, 11B6, Breast cancer-associated gene 1 protein, BCG-1, Hepatocellular carcinoma-associated protein JCL-1, MAGE-D2 antigen,MAGED2 (MAGE Family Member D2) is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. MAGED2 is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in MAGED2 cause a form of transient antenatal Bartter's syndrome. MAGED2 may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by MAGED2 is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants.,MAGD2

Molecular Weight: observerd band 66kDa

Gene ID: 10916

UniProt: Q9UNF1