MSTN antibody (N-Term)

Catalog No. ABIN7221034

This anti-MSTN antibody is a Rabbit Polyclonal antibody detecting MSTN in ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for MSTN antibody (N-Term) (ABIN7221034)

Target: MSTN (Myostatin (MSTN))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSTN antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MSTN Antibody

Binding Specificity: N-Term

Purpose: GDF-8 Polyclonal Antibody

Specificity: GDF-8 Polyclonal Antibody detects endogenous levels of GDF-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GDF-8

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MSTN

Target: MSTN (Myostatin (MSTN))

Alternative Name: GDF-8

Background: Rabbit Anti-GDF-8 Polyclonal Antibody,MSTN, GDF8, Growth/differentiation factor 8, GDF-8, Myostatin,MSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.,Growth

Gene ID: 2660

UniProt: O14793